A COM-B-guided way of life intervention reduces metabolic syndrome in chubby and overweight adolescents: a multiphase research in Vietnam

Metabolic syndrome (MetS) amongst adolescents with chubby/weight problems (OW/OB) is rising quickly in low- and middle-income international locations (LMICs), but proof on theory-driven behavioral interventions stays restricted. To estimate the prevalence and danger elements of MetS in Vietnamese adolescents aged 11-14 years with OW/OB, and to guage the effectiveness of a 12-month way of life intervention grounded within the COM-B mannequin. We carried out a three-phase research: (1) a province-wide cross-sectional survey to find out MetS prevalence; (2) a matched case-control research to establish danger elements; and (3) a school-based COM-B intervention comprising well being schooling, environmental modifications, and motivation enhancement. Adherence was quantified utilizing a six-point scale and categorized as excessive (≥ 75%), reasonable (40-<75%), or low (< 40%). The major end result was MetS decision at 12 months in response to International Diabetes Federation (IDF) pediatric standards; secondary outcomes included anthropometric, biochemical, and behavioral modifications. Of 6,009 college students screened, 2,055 (34.2%) had OW/OB, amongst whom 628 (30.6%; 95% CI, 28.6-32.6) had MetS, with hypertriglyceridemia (87.9%) and low HDL-C (84.4%) being most prevalent. Waist-to-height ratio ≥ 0.46 was the strongest impartial danger issue (OR = 2.96; 95% CI: 1.76-5.00), whereas unique breastfeeding for six months was protecting (OR = 0.45; 95% CI: 0.35-0.58). A 12-month COM-B-guided way of life intervention in 300 OW/OB adolescents with MetS achieved a 71.7% decision fee (95% CI: 66.2-76.7), with vital enhancements in metabolic parameters (triglycerides – 0.41 mmol/L, HDL-C + 0.12 mmol/L, CAP – 29.6 dB/m; all p < 0.001) and well being behaviors (sugar-sweetened beverage consumption – 4.7 occasions/week, display time – 3.6 h/day). High adherence was related to the best cardiometabolic and behavioral positive aspects, supporting a dose-response relationship in keeping with the COM-B framework. A faculty-based COM-B intervention considerably improved MetS and well being behaviors amongst adolescents with OW/OB, with effectiveness various by adherence degree. The mannequin seems possible and scalable in LMIC settings, though longer-term follow-up is required to evaluate sustainability.