Global Fund Partners Demonstrate Unity and Resolve to Sustain Progress and Strengthen Global Health Security – Information Releases

Global Fund Partners Demonstrate Unity and Resolve to Sustain Progress and Strengthen Global Health Security

US$11.34 billion raised amid international challenges marks renewed solidarity and units the stage for a remodeled, extra resilient international well being system.

21 November 2025

JOHANNESBURG/GENEVA – The Global Fund to Fight AIDS, Tuberculosis and Malaria (the Global Fund) held its Eighth Replenishment Summit at the moment in Johannesburg, South Africa, co-hosted by the governments of the Republic of South Africa and the United Kingdom on the margins of the G20 Leaders’ Summit. Despite one of the crucial turbulent geopolitical and financial years in current reminiscence, companions all over the world pledged US$11.34 billion to maintain the combat towards AIDS, tuberculosis (TB) and malaria, save thousands and thousands extra lives, and strengthen methods for well being. 

The Summit additionally marked a renewed dedication to work in another way – embracing a extra agile, country-driven type of partnership that may adapt to a quickly altering international well being panorama, mobilize new donors, and speed up home useful resource mobilization for well being.

The consequence represents a robust demonstration of unity and resolve in a interval outlined by fiscal tightening, battle and international uncertainty. While complete pledges fall wanting the bold goal set within the Investment Case, and a number of other donors have but to substantiate their pledges, this Replenishment nonetheless reaffirms that international solidarity stays robust – and that the world can come collectively to confront these three epidemics and shield future generations.

Renewed management and solidarity

At the Summit, H.E. President Cyril Ramaphosa of South Africa underlined Africa’s rising management in international well being.

“Hosting this Replenishment on African soil for the first time symbolizes how far we have come – and how far we can go,” he stated. “Africa is not only leading in implementation; we are also driving innovation and taking greater responsibility for our own health systems. This partnership embodies solidarity, equity and transformation.”

Five Heads of State and Government, and representatives from 17 international locations, joined the gathering alongside multilateral companions, philanthropies, companies, civil society and neighborhood networks. Their unity despatched a robust message: The combat towards AIDS, TB and malaria will not be over – and international resolve to advance progress stays robust. 

Rt. Hon. Sir Keir Starmer, Prime Minister of the United Kingdom, pressured the worth of investing within the Global Fund.

“In today’s volatile world, we must prioritise spending that makes a genuine difference and supports both growth at home and globally,” he stated. 

“That is why we will continue to support the Global Fund, whose work is at the cutting edge of fighting the world’s deadliest diseases. It is an investment in economic growth and stability, and a prime example of our modern approach to development.”

Strong commitments throughout sectors

Even amid financial headwinds and competing international priorities, companions reaffirmed their confidence within the Global Fund’s influence.

The United Kingdom, as co-host, pledged GBP 850 million for lifesaving prevention, testing and therapy providers, emphasizing that this can be a strategic funding in international and nationwide well being safety and in financial development and stability. South Africa dedicated US$36.6 million, a joint public–personal pledge that features an elevated authorities contribution, which greater than doubled from the final Replenishment, and financing from the South African personal sector amounting to US$10 million, exemplifying Africa’s twin function as each implementer and investor.

The United States, the Global Fund’s largest donor, dedicated US$4.6 billion in recognition of the Global Fund’s function as an important accomplice that scales improvements with a world-class pooled procurement mechanism and helps vital frontline well being care staff. 

Many long-term companions reaffirmed their dedication to the Global Fund and famous the numerous strengths of the Global Fund mannequin. Germany confirmed their pledge of €1 billion, whereas France famous that their help to the Global Fund stays unchanged, however they’d solely be ready to substantiate their pledge subsequent month. Founding donor Canada pledged CAD 1.02 billion. Spain elevated their pledge to €145 million, with Italy pledging €150 million and the Netherlands contributing €146 million. Australia and Norway maintained their respective commitments.

Other donors, akin to India and Ireland, elevated their contributions, reflecting continued management from G20 international locations. Korea maintained its robust dedication to the Global Fund and now qualifies to affix a voting constituency of the Global Fund Board, the primary time this has occurred since 2006. Commitments from the G20 member states reached US$8.96 billion, reflecting the consensus that the Global Fund is a worthwhile funding in advancing international well being. Through these commitments, donors highlighted the Global Fund’s vital function in advancing international well being safety by strengthening surveillance, increasing regional manufacturing capability and supporting international locations to stop, detect and reply to future well being threats.

Various African international locations, all of whom are additionally implementers of Global Fund grants, made solidarity commitments totaling US$51.59 million. They famous their delight in asserting these commitments on the first Replenishment to be held on the African continent. In making their pledges, African leaders highlighted the numerous progress they’re making in financing their very own well being methods to fulfill the wants of their residents.

Private sector driving influence and innovation

The personal sector performed a defining function: The Gates Foundation, the Global Fund’s largest personal donor, pledged US$912 million. The Children’s Investment Fund Foundation (CIFF) pledged an additional US$135 million, taking their complete further dedication to US$200 million for the reason that Seventh Replenishment, a big enhance from their earlier pledges. (RED) continued its practically two-decade partnership with a US$75 million dedication, and different personal donors dedicated a complete of US$201.85 million to carry general Eighth Replenishment help to US$1.34 billion thus far, with extra pledges to come back. Together these investments will speed up entry to new instruments, underpin well being methods strengthening and international well being safety work, and help integration to extend effectivity and enhance outcomes for girls and kids.

A mannequin that works – and evolves

Lady Roslyn Morauta, Chair of the Global Fund Board, stated the result displays each resilience and renewal.

“In a difficult year, this result shows the world’s confidence in our collective model and its enduring power to deliver results,” she stated. “But it also shows our determination to adapt – to work smarter, be more efficient and ensure that every dollar delivers maximum impact.”

The Global Fund mannequin – country-owned, performance-based and community-driven – stays a benchmark for inclusive international well being partnerships. Yet companions agree it should proceed to evolve. In line with the rules reaffirmed by means of the Accra Reset, the Global Fund will proceed to help international locations on the trail to nationally led, nationally financed well being methods, simplify grant processes, and broaden entry to pooled procurement so international locations should buy lifesaving commodities on the lowest value. This evolution additionally depends upon deeper collaboration throughout the worldwide well being ecosystem – together with enhanced collaboration with the World Health Organization, the African Union, Gavi, the Vaccine Alliance and different companions. 

In parallel, the partnership will step up efforts to help the mobilizing of larger home assets for well being, making certain international locations maintain and develop their very own investments to strengthen methods, scale improvements and drive progress towards common well being protection.

“Today’s commitments signal a powerful shift toward partnerships that put countries in the lead, drive innovation, and mobilize sustainable financing for health,” stated H.E. President Bola Ahmed Tinubu of Nigeria. 

“For Nigeria, this aligns with our deepening investment in our own health system – from expanding primary health care to strengthening surveillance and deploying new tools that bring lifesaving services closer to our people. This renewed spirit of solidarity reinforces our determination to build a more resilient, equitable health system and advance universal health coverage, ensuring that every community, no matter how remote, can access quality care.”

Looking forward, the Global Fund is dedicated to accelerating this collaborative shift – transferring from parallel efforts to shared supply pathways, coordinated investments, and country-led platforms that cut back duplication and unlock quicker, extra sustainable influence.

Building on these commitments, Peter Sands, Executive Director of the Global Fund, framed the result as each an achievement and an pressing name for transformation.

“This is a remarkable moment. In a year when many predicted the end of global solidarity, our partners have proven otherwise,” he stated. “Thanks to the steadfast commitment of our donors and partners, this Replenishment delivered a remarkable outcome from a remarkable partnership. It shows what the world can achieve when we stand together, even in the toughest of times.”

“These pledges will save millions more lives, but they also mark a turning point. Our model remains strong – but the world around us is changing. We must keep evolving: becoming smarter, faster and more efficient, and ensuring the entire global health system works better for the people it serves.”

Sands highlighted how innovation at scale – from moveable digital X-rays to AI for TB screening to long-acting HIV prevention to twin lively ingredient insecticide-treated mosquito nets – is reshaping the combat. “Time equals lives; scale equals impact,” he stated, committing to a 20% discount in working prices and a quicker, extra data-driven strategy to supply.

Building resilience and remodeling the best way we work

The funds raised by means of the Eighth Replenishment is not going to solely maintain lifesaving applications, but additionally deepen funding in resilient and sustainable methods for well being. The Global Fund is the most important multilateral grant funder of well being methods strengthening, with over US$2.7 billion invested in oxygen provision, laboratories, information methods and well being workforce coaching in 2024 alone. These investments profit all well being priorities and reinforce international pandemic preparedness.

Sands famous that such effectivity and collaboration can be vital in a tighter fiscal period: “Money will always be tight, so we must be smarter – strengthening countries’ self-reliance by boosting domestic resource mobilization, improving public financial management, supporting the growth of regional manufacturing and leveraging pooled procurement. That’s how we build durable systems that can deliver impact long after this Replenishment cycle.”

Communities stay on the coronary heart

For Cecilia Lodonu-Senoo, talking on behalf of the Communities, Developing Country NGOs and Developed Country NGOs Delegations to the Global Fund Board, the pledges made in Johannesburg carry deep that means.

“For people living with HIV, and for families affected by TB and malaria, these commitments mean access, dignity and hope,” she stated. “Communities have always been at the center of this fight – and we will remain at the heart of what comes next.”

Looking forward: A partnership for a brand new period

The Eighth Replenishment marks the start of a brand new section for the Global Fund – one outlined by transformation, innovation and shared accountability. As remaining pledges are finalized, the partnership will maintain its deal with delivering most influence, making certain assets are translated swiftly and successfully into nation applications. With allocations to be agreed on the February Board assembly, companions are dedicated to sustaining momentum and preserving stress on the system to align ambition with want.

The new Grant Cycle Eight technique over the following three years underscores how the partnership will work smarter – leveraging cutting-edge instruments, strengthening efficiencies and doing extra with much less – whereas supporting governments, communities and companions to construct a worldwide well being ecosystem that’s less complicated, extra coherent and extra conscious of nation priorities.

These investments can even yield substantial financial returns, strengthening workforce productiveness, stabilizing economies and contributing to long-term, inclusive development.

“Together we can end AIDS, TB and malaria,” Sands concluded. “We can build the first generation free from the threat of these diseases – and a global health ecosystem that is faster, fairer and stronger. This Replenishment demonstrates the world’s determination to keep driving forward – proving that even in difficult times, innovation and partnership can prevail.”