Hybrid Knowledgeable System for Life-style Recommendations in Hypertensive Sufferers

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ORIGINAL RESEARCH article

Front. Artif. Intell.

Sec. Medicine and Public Health

  • 1. National University of San Martan, Tarapoto, Peru

  • 2. Universidad Norbert Wiener, Lima, Peru

  • 3. Universidad Nacional de San Martin Tarapoto, Tarapoto, Peru

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Abstract

This research presents a hybrid medical decision-support system for producing customized life-style suggestions in hypertensive sufferers by integrating unsupervised machine studying with rule-based knowledgeable reasoning. Using a real-world dataset of 615 medical data from routine healthcare providers, a preprocessing pipeline combining information imputation, normalization, and dimensionality discount was utilized previous to affected person stratification. Principal Component Analysis (PCA) preserved the dominant latent construction of the information, adopted by Ok-Means clustering, which recognized three clinically interpretable affected person profiles with a Silhouette coefficient of 0.5608. The clustered profiles had been built-in right into a rule-based inference engine structured throughout six life-style intervention domains: bodily exercise, stress administration, diet, sleep patterns, therapeutic adherence, and normal well being behaviors. Recommendations had been generated utilizing a dual-weighting technique prioritizing particular person affected person attributes whereas incorporating cluster-level contextual info. The system was evaluated via blind knowledgeable validation involving cardiologists and medical nutritionists. Agreement between automated suggestions and medical consensus reached 78.3%, with a Cohen’s Kappa coefficient of 0.742, indicating substantial concordance. No statistically vital variations had been noticed between system outputs and knowledgeable judgments (χ² = 8.347, p = 0.908). The outcomes show that combining unsupervised affected person stratification with express medical reasoning allows interpretable and scalable determination help for non-pharmacological hypertension administration, significantly in healthcare environments with restricted labeled information

Summary

Keywords

Clinical decision support, Hybrid expert system, Hypertension management, lifestyle recommendations, patientstratification, unsupervised learning

Received

23 January 2026

Accepted

04 March 2026

Copyright

© 2026 Valles-Coral, Pinedo, Richard, Navarro-Cabrera, Quintanilla-Morales, Sarita, Valverde-Iparraguirre, Sanchez-Dávila and Gonzalez-Gonzalez. This is an open-access article distributed below the phrases of the Creative Commons Attribution License (CC BY). The use, distribution or replica in different boards is permitted, offered the unique creator(s) or licensor are credited and that the unique publication on this journal is cited, in accordance with accepted educational observe. No use, distribution or replica is permitted which doesn’t adjust to these phrases.

*Correspondence: Miguel Angel Valles-Coral

Disclaimer

All claims expressed on this article are solely these of the authors and don’t essentially symbolize these of their affiliated organizations, or these of the writer, the editors and the reviewers. Any product which may be evaluated on this article or declare which may be made by its producer will not be assured or endorsed by the writer.


This web page was created programmatically, to learn the article in its unique location you’ll be able to go to the hyperlink bellow:
https://www.frontiersin.org/journals/artificial-intelligence/articles/10.3389/frai.2026.1794925/full
and if you wish to take away this text from our website please contact us