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Investigators from Emory University have elevated their cardiac studies to remarkable levels. The group has recently published results from a study utilizing the International Space Station (ISSInternational Space Station) National Laboratory in the prestigious journal Biomaterials. This study, which was dispatched to the ISS on NASA’s SpaceX Crew-8 mission, investigated the impacts of microgravityThe condition of perceived weightlessness created when an object is in free fall, for example when an object is in orbital motion. Microgravity alters many observable phenomena within the physical and life sciences, allowing scientists to study things in ways not possible on Earth. The International Space Station provides access to a persistent microgravity environment. on three-dimensional clusters of cardiac muscle cells.
By examining the growth and functionality of cardiac muscle cells in the distinct environment of space, the research group aspires to transform cell therapy, paving the way for innovative methods to heal damaged hearts in individuals on Earth. Findings from the study indicated that space travel enhances the expression of genes related to stress response and cell survival. Gaining insight into these changes induced by space travel might foster new approaches to generating cardiac muscle cells on Earth that are more resilient to stress and durable when transplanted into patients, which is vital for effective regenerative treatments.
This pioneering research, which builds upon earlier studies funded by the ISS National Lab, showcases the effectiveness of space-based investigations in tackling some of the most urgent health issues faced by humanity. For over a decade, the Emory team, under the guidance of Chunhui Xu, has harnessed the unique microgravity environment to propel cardiac research forward.
The investigation was financially supported by the U.S. National Science Foundation, which plays a crucial role in providing essential backing for fundamental science across various domains, including tissue engineering and transport phenomena. To discover more, please visit Emory University’s news announcement regarding this thrilling progress.
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