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August 13, 2025
2 min learn
These Spiders Puke Up Toxic Digestive Fluid to Marinate Their Prey Alive
Without a venomous chunk, some spiders use a disturbing second possibility to arrange their meals

Stefan Sollfors/Alamy Stock Photo
You don’t at all times want a ebook or film for a great horror story. Sometimes, when you dare look intently sufficient, yow will discover one in your personal yard. Researchers have simply confirmed the internal workings of a brutal food-prep method some spiders use, wrapping their web-snagged prey tightly in silk strands, then puking up poisonous digestive fluids to soak the whole package deal to marinate their meal alive.
Spiders from the Uloboridae household, normally just some millimeters lengthy, have puzzled scientists as a result of they appeared to lack venom—a substance that’s widespread amongst spiders and “really linked to their evolutionary success,” says Alex Winsor, a neuroethologist on the University of Massachusetts Amherst who wasn’t concerned within the new analysis.
And there was one other thriller. Uloboridae spiders have been already recognized to wrap their prey in a whole lot of meters of silk after which regurgitate on them, however researchers hadn’t absolutely pinned down the perform of their dramatic vomit. Intrigued, a examine crew took a better have a look at how these predators put together a snack for themselves. The findings have been revealed in BMC Biology.
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By analyzing one species known as Uloborus plumipes, the researchers confirmed that these spiders lack venom glands and thus are unable to manage venom within the traditional spider manner: injecting it into their prey with a fanged chunk. But the scientists did discover genes actively producing toxinlike proteins within the spiders’ digestive system—notably within the midgut space—and these potential toxins “appear to be very strong,” says examine co-author Giulia Zancolli, an evolutionary biologist on the University of Lausanne in Switzerland.
Injecting these digestive fluids into fruit flies within the laboratory proved their excessive toxicity: simply 230 nanograms—billionths of a gram—killed greater than half the flies inside an hour. The researchers theorize that these spiders do certainly marinate their prey to demise this manner. Strangely, some spiders from different households that kill with the standard venomous bites are additionally recognized to have toxins of their digestive fluids, Zancolli says. This truth raises what she calls a “fascinating question”: What position do these substances play for species exterior the Uloboridae household?
The examine’s discovering “solves a puzzle within spider biology,” Winsor says. A subsequent step, he provides, might be to research whether or not digestive-system toxins seem in different animal species, resembling some lizards. “If these compounds do have some special ability to subdue insects, then you might expect them to emerge in other groups of animals,” Winsor says. If that proves true, “then maybe these are a recurring answer in the animal kingdom.”
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