Peru Requires Yellow Fever Vaccination for Most Guests — Vax-Before-Travel

Peru’s Ministry of Health (MINSA) immediately introduced that it’s urging each home and worldwide vacationers to prioritize yellow fever prevention when planning journeys to the nation’s rural and jungle areas, that are recognized to be endemic for the mosquito-transmitted illness.

Given the continuing threat of transmission, MINSA said in a press release on January 10, 2026, that the best safety towards yellow fever is vaccination.

During the primary half of 2025, Peru reported 35 confirmed human circumstances of yellow fever, together with 12 deaths (case fatality price of roughly 34%).

The areas with the very best threat embrace Amazonas, San Martín, Junín, Ayacucho, Cusco (rural areas solely), Loreto, Madre de Dios, Huánuco, Pasco, Puno, and Ucayali. Urban areas, reminiscent of town of Cusco, Machu Picchu, and the Inca Trail, aren’t included in these warnings.

In Peru, MINSA recommends that vacationers obtain the vaccine at the very least 10 days earlier than visiting at-risk areas.

The yellow fever vaccine (Stamaril, YF-Vax) is free, protected, and gives lifelong safety with only a single dose. It is advisable for people aged 15 months to 59 years.

In 2025, between 3 and 5 million folks visited Peru, with over 1 million touring to Machu Picchu.

While Peru doesn’t require proof of yellow fever vaccination for entry in all circumstances, guests ought to seek the advice of a healthcare supplier to substantiate their eligibility for immunization.

Additionally, vacationers might have to current an International Certificate of Vaccination or Prophylaxis, generally known as the “yellow card,” as proof of vaccination at some entry factors.

When departing from the United States for Peru, the Centers for Disease Control and Prevention recommends the YF-Vax vaccine for all vacationers ≥9 months outdated touring to areas under 7,550 ft elevation in at-risk areas. This vaccine is commercially provided at journey clinics in 2026.