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“Our results show that it is not just the number of conditions that matters. The combination of conditions can also influence how well a preventive lifestyle intervention works,” says Davide Liborio Vetrano , affiliate professor of Geriatric Research on the Aging Research Center , Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and first creator of the research.
According to the researchers, the outcomes could assist be certain that preventive programmes sooner or later are higher tailor-made to the person’s illness profile.
“The study suggests that a more personalised strategy could make it easier to target the right intervention to the right person and thereby prevent disability in older people,” says Davide Liborio Vetrano.
At the identical time, the researchers emphasise that the research is a post-hoc evaluation of a scientific trial and that the outcomes must be confirmed in different research and in broader teams of older folks.
The research was carried out as a part of the European SPRINTT venture, involving researchers from a number of universities and analysis institutes in 11 European international locations. The analysis was funded, amongst different sources, by the Innovative Medicines Initiative (IMI) and with help from the Swedish Research Council and Karolinska Institutet. The researchers state that they don’t have any conflicts of curiosity.
Publication
Multimorbidity patterns influence mobility disability prevention in frail older adults from the SPRINTT trial . Vetrano DL, Gregorio C, Triolo F, Soraci L, Cherubini A, Tosato M, von Haehling S, Marzetti E, Landi F, Calvani R., Nature Aging. 2026. DOI: 10.1038/s43587-026-01188-x.
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